This conference has now taken place.
This translational event focused on mechanisms of immunity in the CNS, clinical consequences of autoimmunity, and experimental models to study anti-NMDA receptor encephalitis and other neurological diseases. 255 delegates benefited from presentations of cutting-edge clinical and laboratory findings by both the invited speakers and poster presenters, which enabled authoritative discussion of future research into immunological mechanisms of brain disease.
Of 66 posters presented at the conference, the winning posters selected were:
A mouse model of T-cell-mediated autoimmune narcolepsy
Bernard-Valnet R1, Queriault C1, Yshii L1, Pignolet B1, Dauvilliers Y2, Peyron C3, Liblau R1
1Inserm U1043, France; 2Department of Neurology, CHU Guy de Chaillac, INSERM U1061, France; 3INSERM U1028, CNRS, UMR 5292, Center for Research in Neuroscience of Lyon, France
Multicentre comparison of European diagnostic AQP4 antibody assays Waters P1, Reindl M2, Saiz A3, Siva A4, Aktas O5, Saschenbreker S6, Vincent A1, Marignier R7 1University of Oxford, UK; 2Medical University of Innsbruck, Austria; 3Hospital Clinic IDIBAPS and Universitat de Barcelona, Spain; 4Istanbul University Cerrahpasa School of Medicine, Turkey; 5Heinrich-Heine-University Düsseldorf, Germany; 6Euroimmun AG, Germany; 7Lyon Neurosciences Research Centre, France
Isoaspartylation triggers autoimmunity in small cell lung cancer
Laird-Offringa IA1, Pulido MA1, Derhartunian MK1, Qin Z2, Chung EM1, Lee DS1, Woodham AW1, Tsou JA1, Klooster R3, Verschuuren JJGM3
1University of Southern California, USA; 2University of California at Irvine; USA,3Leiden University, The Netherlands
Lisa Boulanger, Princeton University, USA
Susannah Cahalan, Author, Brain on Fire, USA
Graham Collingridge, Centre for Synaptic Plasticity, University of Bristol, UK
Yanick Crow, Paris Descartes University, France, and University of Manchester, UK
Josep Dalmau, University of Pennsylvania, USA and University of Barcelona, IDIBAPS, and ICREA, Spain
Francesc Graus, University of Barcelona and IDIBAPS, Spain
Laurent Groc, Interdisciplinary Institute for Neuroscience, Bordeaux, France
Daniel Javitt, Columbia University College of Physicians and Surgeons, USA
Melike Lakadamyali, Advanced Fluorescence Imaging and Biophysics Group, ICFO, Spain
Vanda Lennon, Mayo Clinic College of Medicine, Rochester, MN, USA
Stuart Lipton, Sanford-Burnham Medical Research Institute, The Scripps Research Institute, and University of California, San Diego, USA
Rafael Maldonado, Pompeu Fabra University, Spain
Isabel Perez-Otano, University of Navarra Medical School, Spain
Richard Ransohoff, Biogen Idec, USA
Kevin Rostasy, Medical University of Innsbruck, Austria
David Sulzer, Columbia University Medical Center, New York, USA
Maarten Titulaer, Erasmus Medical Center, Rotterdam, The Netherlands
Hartmut Wekerle, Max Planck Institute of Neurobiology, Germany
The first case series of patients with anti-NMDA receptor encephalitis, an autoimmune disorder of the brain, were reported in 2007. The NMDA receptor has a crucial role in synaptic function, and this novel disease is not only providing insights into the function of the receptor in humans, but also into understanding immunological mechanisms of brain disease.
With this event, The Lancet Neurology had the opportunity to disseminate cutting-edge clinical and laboratory findings, and to facilitate an authoritative discussion of autoimmune targets in the CNS, such as the NMDA receptor, paving the way for future research into immunological and synaptic mechanisms of brain disease.
The event had a translational focus, covering mechanisms of immunity in the CNS, clinical consequences of autoimmunity, and experimental models to study anti-NMDA receptor encephalitis and other neurological diseases.
Sponsors & Exhibitors